Evaluate all ROls in a user defined sub-volume at once.
The ROI volume as well as the maximum and mean values (SUV or measured units eg. Bq/ccm) can be accessed with a few mouse clicks. The ROls can be displayed in three views: the orthogonal view, the multiple plane view and the maximum intensity projection. The direct slice navigation and the rich choice of colormaps provide an efficient way of data evaluation.
The ROVER strategy for automatic 3D ROI determination is based on an initial user-guided gross differentiation between target (the ROls) and background (everything else) within each user defined sub-volume. To this end, the user only has to adjust a starting threshold. In the next step, an automatic algorithm then iteratively adjusts the threshold and subtracts the background. In effect, the resulting ROIs are essentially independent of the initial guess of the threshold. The resulting ROI volumes are good estimates of the true volumes.
For direct comparison the ROI volumes as well as related quantities as maximum SUV can be visualized in the form of bar plots.
ROVER allows easy generation of time acivity curves which can exported for further evaluation
(1) PET-Zentrum, Helmholtz-Zentrum Dresden-Rossendorf, Germany
(2) Klinik und Poliklinik für Nuklearmedizin, Universitätsklinikum Carl Gustav Carus, Dresden, Germany